|
|
 |
 |
 |
|
 |
 |
Musculo-Skeletal (1/3)
Animal Health Trust - Newmarket
Dept. of Clinical Vet Medicine
Wright, I. M.
CLINICAL AND RADIOLOGICAL INVESTIGATION OF A SURGICAL TREATMENT OF EQUINE NAVICULAR DISEASE.
Abstract: Treatment of clinical cases of navicular disease by navicular suspensory desmotomy and six monthly re-evaluation.
Animal Health Trust - Newmarket, Suffolk, England CB8 7DW
Dept. of Clinical Studies
Mayhew, I.G.; Washbourne, J.R.
CENTRAL AND PERIPHERAL NEUROMUSCULAR CONDUCTIONS IN HORSES AND THEIR ROLE IN PERFORMANCE.
Abstract: The project involves the measurement of sensory and motor conductions through the brain, spinal cord, peripheral nerves and muscles of horses under standerdised conditions utilising modern electrodiagnostic equip- ment. The influence that such variables as ambient temperature, age, sex, breed, drugs, training and performance status and spinal cord disease have on the objective recorded characteristics of neuromuscular conduction will be defined.
Animal Health Trust - Newmarket, Suffolk, England CB8 7DW
Dept. of Physiology
Gray, J.A.;* Harris, P.A.;* Robbins, S.P. *Rowett Research Institute
THE DETECTION AND MONITORING OF BONE DISORDERS IN THE THOROUGHBRED.
Abstract: The development of methods for the monitoring of bone formation and resorption in the horse. This may enable horses with potential skeletal problems to be identified before clinical signs become apparent, thus enabling appropriate corrective measures to be taken. * Rowett Research Institute, Aberdeen, AB2 9SB.
Animal Health Trust - Newmarket, Suffolk, England CB8 7DW
Dept. of Physiology
Harris, R. C.; Dunnett, M.
CARNOSINE IN EQUINE MUSCLE: ITS DISTRIBUTION, METABOLISM AND PHYSIOLOGICAL ROLE.
Abstract: A 3 year investigation into the distribution of carnosine in different muscles of the horse and different muscle fibre types, into factors governing its synthesis and breakdown, and its quantitative importance in the regulation of the intracellular acid-base environment during fast exercise.
Animal Health Trust - Newmarket, Suffolk, England CB8 7DW
Dept. of Physiology
Harris, R. C.; Harris D. B.
ATP DISTRIBUTION IN DIFFERENT MUSCLE FIBRE TYPES IN THE THOROUGHBRED HORSE FOLLOWING SUSTAINED FAST EXERCISE.
Abstract: A two year project to examine the extent of ATP loss in different muscle fibre types isolated from the middle gluteal muscle following fast ex- ercise. Catastrophic loss of ATP in a small percentage of fibres could explain post exertional muscle stiffness and other symptoms associated with "tying-up".
Animal Health Trust-Newmarket, Suffolk, England CB* 7DW
Wood
AN EPIDEMIOLOGICAL STUDY OF FATAL INJURY AT UK RACECOURSES.
Abstract: The aims of the study are to determine (1) the incidence of death and severe injury on British racecourses and to evaluate statistically whether the rates appear to be changing in time: (2) whether there are differences in the probability of death and severe injury on different racecourses after the effects of different risk factors such as going, the type of race, the length and speed of race have been taken into account; (3) whether any differences in rates between racecourses are associated with racecourse characteristics;
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Animal Health Trust
Dyson, S. J.
SUSPENSORY LIGAMENT DESMITIS.
Abstract: The forelimb suspensory ligaments of approximately 300 clinically normal horses have been examined ultrasongraphically. The horses represent a broad range of ages, types and occupations. Each horse is subjected to a clinical assessment including documentation of any conformational abnormalities. The suspensory ligaments were examined from immediately distal to the carpus and at one centimeter increments to the level of their bifuraction. Images were re- corded on Polaroid film for subsequent analysis. The deep digital flexor tendon
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Animal Health Trust
Wright, I. M.; Kidd, L. J.; Thorpe, B. J.
NAVICULAR DISEASE.
Abstract: The aim of this project is to study the pathophysiology of navicular disease by examining post-mortem material from horses with clinical signs of the condition. The gross pathological, radiological and histopatho- logical features of the navicular bone and adjacent structures in these animals are compared with immature, age, and age and use matched controls. The control animals have no history of forelimb lameness. To date distal limbs have been collected from 35 clinical cases. (more on next page)
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Animal Health Trust - Dept. of Clinical Studies
Dyson, S.
UPPER FORELIMB LAMENESS.
Abstract: Investigation of causes of forelimb lameness.
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Animal Health Trust - Dept. of Clinical Studies
Kold, S.
ASPECTS OF BONE GRAFT INCORPORATION IN HORSES.
Abstract: Qualitative and quantitative aspects of bone graft incorporation are being investigated from both clinical and experimental materials.
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Animal Health Trust - Dept. of Clinical Studies
Kold, S.
BONE PATHOLOGY OF INDUCED STIFLE BONE CYSTS.
Abstract: Subchondral cystic lesions and cartilaginous defect which might result in the development of typical subchondral bone cysts, have been created in a number of ponies. Autogenous and homogenous bone grafts will be used to evaluate the degree of osseous healing.
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Dept. of Clincal Studies
Dyson, S.
THE DISTAL INTERPHALANGEAL JOINT SYNDROME.
Abstract: Clinical, radiographic and post mortem assessment of pain associated with the distal interphalangeal joint and related structures.
Animal Health Trust/Newmarket, Suffolk, England CB8 7DW
Dept. of Clincal Studies
Dyson, S.
THE EQUINE SUSPENSORY (INTEROSSEUS) LIGAMENT.
Abstract: Ultrasonographic and histologic investigations of the suspensory ligament of the forelimb in horses of all types and ages.
Auburn University
College of Veterinary Medicine
Hanson, R. R.
EVALUATION OF THE INFLUENCE OF COMPLEX CARBOHYDRATES ON THE PATHOGENESIS OF NAVICULAR DISEASE IN THE HORSE.
Abstract: This is a double-blinded clinical trial to evaluate the effectiveness of cosequin in the treatment of navicular disease in the horse.
Auburn University
College of Veterinary Medicine
Hanson, R.R.; Kincaid, S.A.
MRI AND MORPHOLOGIC ANATOMY OF THE NORMAL EQUINE HOCK JOINT.
Abstract: The gross and morphologic anatomy with magnetic resonance imaging is correlated in the normal equine hock. Imaging is complete, sectioning and photography of gross sectioning is complete. Correlation of samples is underway.
Beaufort Cottage Stables - University of Cambridge High Street, Newmarket, United Kingdom
Bathe, A.
ASSOCIATIONS BETWEEN STRUCTURE, FUNCTIONAL ADAPTATION AND INJURY IN THE BONES OF THE DISTAL TARSUS IN THE THOROUGHBRED RACEHORSE.
Abstract: NOT REPORTED.
Bristol, University of - Langford, Bristol, UK BS18 7DU Home of Rest for Horses
Dept. of Anatomy - Langford
Goodship, A.E.; Wilson, A.M.
THE APPLICATION OF HOOF-GROUND PRESSURE DISTRIBUTION ANALYSIS TO FARRIERY PRACTICE AND PREVENTION AND TREATMENT OF DISEASE PROCESS OF THE FOOT.
Abstract: NOT REPORTED.
Bristol, University of - Langford, Bristol, UK BS18 7DU Horserace Betting Levy Board
Dept. of Anatomy - Langford
Goodship, A.E.; Wilson, A.M.; Bailey, A.J.
EXTRACELLULAR MATRIX CHARACTERISTICS AND TENOCYTE FUNCTION IN RESPONSE TO SPECIFIC EXERCISE.
Abstract: Response of tendon to functional demand or the initial changes that ultimately result in degeneration and clinical injury. This proposal addresses the prerequisite to rational treatment and training regimes, namely the elucidation of the basic biological behavior of tendon tissue in response to exercise. Combining expertise in adaptive responses of skeletal tissue, collagen chemistry and molecular biology the proposal aims to characterise the effects on collagen metabolism of specific levels of exercise.
Bristol, University of - Langford, Bristol, UK BS18 7DU Home of Rest for Horses
Dept. of Anatomy - Langford
Wilson, A.M.; Williams, G.E.
CHARACTERISTICS OF THE BIOMECHANICS OF EARLY NAVICULAR DISEASE AND ITS TREATMENT BY COMPLEMENTARY FARRIERY AND PHARMACOLOGICAL TECHNIQUES.
Abstract: Foreceplate investigation of navicular disease induced gait abnomalities and its treatment using bisphosphonates.
Bristol, University of - Langford, Bristol, UK BS18 7DU
Dept. of Veterinary Clinical Science
Barr, A.R.S.; Duance, V.C.
ARTICULAR SURFACE STRUCTURE, INJURY AND REPAIR.
Abstract: An investigation of the collagenous structure of equine articular cartilage and the effect of growth factors on cells that may contribute to articular surface repair.
Bristol, University of - Langford, Bristol, UK BS18 7DU
Dept. of Veterinary Clinical Science
Fuller, C.; Barr, A. Dieppe, P.A.
OSTEOARTHRITIS IN THE HORSE.
Abstract: An investigation of synovial fluid markers and 8-scintigraphy in the assessment of equine osteoarthritis.
California Polytechnic University - Pomona, CA 3801 W. Temple Ave.
Equine Research Center
Lindstrom,; Adams,; Hallett,; Matthews
COMPARISON OF VARIOUS THERAPIES ON COOLING THE EQUINE FORELEG.
Abstract: This project was presented at eh Equine Nutrition and Physiology meetings in Fort Collins in 1987. Mr. Adams has completed his thesis and Mr. Lindstrom is extending the study.
California State Polytechnic University - Pomona, CA
Equine Research Center
Linstrom, B.; Hackett, G.
COLD THERAPY EFFECTS ON THE EQUINE FORELEG.
Abstract: Examination of varying cooling techniques on five Arabian horses' lower foreleg of varying ages and both sexes. The experimental design will examine if any significant differences in the ability to constrict the blood flow by lowering the surface temperature of the limb through various treatments on the five horses. The five treatments include a control (no cooling application), standing tap water (15 degrees C), circulating tap water (15 C), standing ice water (1 degree C) and circulating ice water (1 C).
California State Polytechnic University - Pomona, CA
Equine Research Center
van Bruekelen, F; Wickler, S.
MUSCLE MASS AND OXIDATIVE CAPACITY CHANGES ASSOCIATED WITH DISUSE.
Abstract: This study deals with muscle atrophy with disuse. Ramifications of this type of research can be wide spread, and applied to various species. This project uses the Golden Mantle Gound Squirrel as a model, looking at disuse through the animals' changes during hibernation. With increased research in this area perhaps more information on the horse's response to lay-ups, after extensive training would become available. This study is currently in the data collection stages, with some data analyzed.
California State Polytechnic University - Pomona, CA 91768
Equine Research Center
Wickler, S. J.; Greene, H.
MUSCLE FIBER TYPES IN MULES.
Abstract: Muscle fibertyping was done on the gluteus medius of both quarterhorses and mules used under similar circumstances in a packing operation. Mules had a greater percentage of slow oxidative fibers and a greater percentage of fast high oxidative fibers. Results are being presented at the Equine Nutrition and Physiology Society Meetings in 1995.
California, University of - Davis, CA 95616
Hildebrand, S.V.; Holland, M.; Hill, T.
NEUROMUSCULAR AND CARDIOVASCULAR EFFECTS OF CONSTANT INFUSION ATRACURIUM HALOTHANE - ANESTHETIZED HORSES.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
Nyland, T.; Penninck, D.; Lloyd, K.
ULTRASONOGRAPHY OF THE EQUINE STIFLE.
Abstract: NOT REPORTED.
California, University of - Davis, CA 95616
Pascoe, J.R.; Lloyd, K.; Stover, S.
PHARMACOKINETICS OF GENTAMICIN SULFATE AFTER INTRA-ARTICULAR ADMINISTRATION OF GENTAMICIN SULFATE AND SODIUM BICARBONATE IN AN EQUINE SEPTIC JOINT MODEL.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
Pascoe, J.R.; Markel, M.; Pool, R.
REPAIR OF OBLIQUE HUMERAL FRACTURES IN THE ADULT HORSE.
Abstract: NOT REPORTED.
California, University of - Davis, CA 95616 Equine Research Lab - School of Vet Medicine
Anatomy Dept.
Stover; Les
RESURFACING JOINT DEFECTS WITH AUTOGENOUS STERNAL OSTEOCHONDRAL GRAFTS.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
Department of Surgery
Hildebrand, SV.; Arpin, DA.
MALIGNANT HYPERTHERMIA AS A CAUSE OF EQUINE ANESTHETIC AND EXERCISE INDUCED MYOPATHY.
Abstract: To determine whether Malignant Hyperthermia (MH) is a factor in equine myopathy, we have modified the halothane-caffeine contracture test to identify equine muscle with the MH defect. To date, this test is the most reliable for the identification of MH in humans and swine. Serum biochemistry, histochemistry, and fiber typing are also being done on muscle biopsies studied. Correlation of equine myopathy and MH will enable us to better predict and treat myopathy, and advise breeding programs, since MH is hereditary.
California, University of - Davis, CA 95616 Equine Research Lab - School of Vet Medicine
Dept. of Anatomy
Stover; Sutthipong
STEROID ASSOCIATED BONE LOSS IN HORSES.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
Dept. of Pathology
Pool, R.R.; Stover, S.; Pascoe, J.R.
EVALUATION OF AUTOGENOUS OSTEOCHONDRAL GRAFT INCORPORATION IN WEIGHTBEARING OSTEOCHONDRAL DEFECTS IN THE HORSE.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Vet Med - Depts of Anatomy & Cell Biology
Stover, Susan M.
CASE-CONTROL STUDY OF RISK FACTORS FOR FATAL MUSCULOSKELETAL INJURIES IN RACEHORSES.
Abstract: The longterm goal of this project is to reduce the incidence of fatal musculoskeletal injuries in racehorses by the identification of factors that predisposes horses to these injuries and the subsequent development of recommendationns for the prevention of these injuries. The objective is to identify racing and training related factors that are associated with high risk for racehorses to develop a fatal musculoskeletal injury. A case-control study of racehorses with and without musculoskeletal injuries will be performed.
California, University of - Davis, CA 95616
School of Vet Medicine
Cardinet; Valberg
GLYCO(GENO)LYTIC ABNORMALITIES OF SKELETAL MUSCLE IN EXERTIONAL MYOPATHIES OF THE HORSE.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Vet Medicine
Cullor; Hughes; Couto; Cheung
THE USE OF NATURAL ANTIBIOTICS (DEFENSINS) AGAINST EQUINE UTERINE, OCULAR, AND SYNOVIAL PATHOGENS.
Abstract: The investigation is directed towards the use of "natural antibiotics" against assorted bacterial pathogens of the equine. The preliminary experiments will involve in vitro killing assays of many bacteria. When we define the efficacy of the microbicidal activity in our buffer system, we will expand the research to assess the antimicrobial activity of the defensins in the presence of differing bilological fluids (i.e. tears, uterine fluid, synovial fluid, etc.)
California, University of - Davis, CA 95616
School of Vet Medicine
Meagher; Pool
HEALING OF BONE AND ARTICULAR CARTILAGE FOLLOWING ARTHROSCOPIC REMOVAL OF NATURALLY OCCURRING OSTEOCHONDRAL CHIP FRACTURES IN THOROUGHBRED RACE HORSES.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Vet Medicine
Meagher; Pool
THE HISTOPATHOLOGICAL STUDY OF EQUINE OSTEOCHONDRAL FRAGMENTS REMOVED ARTHROSCOPICALLY FROM CLINICAL CASES AT THE VMTH.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Vet Medicine
Pool, R.R.; Meagher, D.M.
HISTOPATHOLOGIC FINDINGS IN ARTHROSCOPIC SPECIMENS USED IN UNDERSTANDING THE PATHOGENESIS OF JOINT DISEASE IN HORSES: A CLINICO- PATHOLOGIC STUDY OF HORSES WITH SUBACUTE AND CHRONIC LAMENESS.
Abstract: This project has been combined with US 88-055 because of funding.
California, University of - Davis, CA 95616
School of Vet Medicine
Pool; Ferraro; Meagher
HISTOPATHOLOGIC STUDY OF OSTEOCHONDRAL FRAGMENTS REMOVED DURING ARTHROSCOPIC SURGERY OF JOINTS IN RACEHORSES WITH SIGNS OF ACUTE JOINT INJURY.
Abstract: This ongoing project studies the gross and microscopic appearances of fractured bone and cartilage chips removed from the knee (carpus) of racing Thoroughbred horses. The researchers hope to clarify this chronic process to enhance the ability to detect impending disease and prevent its occurrence.
California, University of - Davis, CA 95616
School of Vet Medicine - Dept. of Anatomy
Stover; Les
A KINEMATIC, HISTOLOGIC, AND FINITE-ELEMENT INVESTIGATION INTO THE ROLE OF THE SECOND AND FOURTH METACARPAL BONES IN THE BIOMECHANICS OF THE EQUINE METACARPUS.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab - Neonatal
Carlson, G.; Madigan, J.; Golenz, R.; Craychee, T.
THE DEVELOPMENT OF A SAFE AND PRACTICAL INTRAOSSEOUS INFUSION TECHNIQUE IN NEONATAL FOALS.
Abstract: Intravenous fluid therapy is an important component in treating critically ill foals with circulatory collapse due to severe dehydration or shock. This study will determine if intraosseous infusion will be potentially useful in the treatment of neonatal foals by providing an alternative route to the circulatory system. The goal of this study is to develop a safe, practical and effective technique for intraosseous infusion in neonatal foals (first two weeks of life).
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab - Neonatal
Madigan, J.; Pintchuk, P.
THE PRESENCE OF RELAXIN AND RELAXIN BINDING SITES IN THE NEONATAL FOAL AND THE RELATIONSHIP OF RELAXIN TO CONTRACTED TENDONS IN THE FOAL.
Abstract: Relaxin is a natural hormone produced by the placenta of the pregnant mare. This study will investigate the potential role of relaxin in the neonatal foal. The objectives of this study are: 1) quantitatively measure levels of relaxin in the normal neonatal foal immediately following birth and over the first three days of life; 2) correlate levels of relaxin with flexural angles of the limbs in foals during the first three days of life; 3) determine if relaxin receptors are present in the tendons and ligaments of newborn foals;
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
Meagher, D.; Vatistas, N.; Pool, R.; Wright, I.; Bennett, D.
THE INVESTIGATION OF SOME OF THE FACTORS INVOLVED IN JOINT RELATED INJURIES IN HORSES.
Abstract: In this study, researchers will evaluate a group of horses with lameness attributable to the knee joint. While under anesthesia, synovial fluid and membrane samples will be obtained arthroscopically from specific areas within the joint. The samples will be examined microscopically and biochemically to ascertain the response of the synovial membrane to naturally occurring insults. The results will also be correlated to changes in cell numbers and chemicals in the synovial fluid.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
O'Brien, T.; Koblik, P.; Kaneps, A.
CHARACTERIZATION OF COFFIN BONE SOLAR MARGIN LESIONS IN THOROUGHBRED FOALS USING COMPUTED TOMOGRAPHY, MAGNETIC RESONANCE IMAGING, RADIOGRAPHY AND HISTOLOGIC EXAMINATIONS.
Abstract: The aim of this study is to determine the relative sensitivity of non-invasive computed tomography, magnetic resonance imaging, and radiography for detecting coffin bone solar margin lesions.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
Pascoe, J.; Snyder, J.; Vatistas, N.
INVESTIGATION OF A MODIFIED SURGICAL TECHNIQUE FOR THE TREATMENT OF LOCKING STIFLES.
Abstract: The goal of this study is to compare the standard surgical technique of repairing locking stifles with the modified surgery under controlled conditions. Because surgery to treat locking stifles is performed fairly commonly in horses, it is important to establish the merits of a modified technique in preventing the development of debilitating lameness.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
Pool, R.; Stover, S.; O'Brien, T.
PATHOGENESIS OF THIRD CARPAL BONE DISEASE AND FRACTURE IN RACING THOROUGHBRED HORSES.
Abstract: This study will utilize third carpal bones from 100 racing Thoroughbreds obtained through the California Horse Racing Board Post-Mortem Program. The goal of this project is to understand the mechanisms of third carpal bone fractures so that strategies can be developed to prevent their occurrence.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
Stover, S.; Benton, H.; MacDonald, M.
STUDY OF NATURALLY OCCURRING GROWTH FACTORS FOR THE PREVENTION AND TREATMENT OF ARTHRITIS.
Abstract: The specific aim of this study is to evaluate the influence of natural growth factors in cultures established from equine cartilage and synovial cells. The ultimate goal of this study is to develop new ways of inhibiting and treating joint disease in the horse.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
Stover, S.; McDuffee, L.; Taylor, K.
A NEW METHOD FOR REPAIR OF BROKEN TIBIAS.
Abstract: The purpose of this study is to evaluate the use of an interlocking nail that is used in human medicine for fracture repair. Tibias from cadaver horses will be obtained and a fracture created. The tibia will be repaired with either an interlocking nail or bone plates and screws. The strength and stiffness and energy required to break the repaired bones, will be measured and compared using a mechanical testing system that stimulates the type of stresses the equine tibia might incur.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Orthopedics
Stover, S.; Taylor, K.
STUDY OF THE DEVELOPMENT OF AND FACTORS PREDISPOSING TO FRACTURE OF THE HUMERUS IN RACEHORSES.
Abstract: The objective of this study is to better understand the development of damage to the humerus that predisposes it to fracture completely and ultimately, to design preventive strategies to decrease the number of poetentially affected racehorses in the future.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Performance
Cardinet, G.; Valberg, S.;
THE FORMATION, STORAGE AND BREAKDOWN OF MUSCLE SUGAR (GLYCOGEN) IN HORSES WITH TYING-UP: EFFECT OF DIET AND SEX HORMONES.
Abstract: The purpose of this study is to determine if tying-up is caused by a deficiency of energy in muscle cells during exercise due to the inability to breakdown a highly branched glycogen. Specifically, this study will examine the amount of glycogen, its structure and the enzymes involved in its formation and degradation in 1) horses with tying-up compared to healthy horses, 2) horses on a high grain diet, and 3) mares with hormone supplement, estrogen and progesterone.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Performance
Case, J.; Stover, S.
ANALYSIS OF RISK FACTORS ASSOCIATED WITH BREAKDOWNS IN CALIFORNIA RACEHORSES.
Abstract: The primary goal of this study is to create an information system providing a storehouse of data which can be used to identify risk factors associated with catastrophic injury or disease in California racehorses. Results from this study will provide new information on the reasons for racehorse break- downs, which may lead to preventive measures and significant decreases in catastrophic injuries.
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Performance
Jones, J.; Pascoe, J.; Tyler, W.; Valberg, S.; Spier, S.
EFFECTS OF MITOCHONDRIAL OXIDATIVE ENZYME AND MUSCLE GLYCOLYTIC ENZYME DEFECTS, AND HYPERKALEMIC PERIODIC PARALYSIS (HYPP) ON EXERCISE CAPACITY IN THE HORSE.
Abstract: This study will include testing of a Thoroughbred with a mitochondrial cytochrome enzyme (oxygen utilizing) deficiency, several Thoroughbreds with glycogen (muscle sugar) branching enzyme or glucose-6-phosphate enzyme deficiencies (non-oxygen sources of energy), and a group of Quarter Horses with hyperkalemic periodic paralysis or HYPP (high potassium concentrations causing bouts of paralysis).
California, University of - Davis, CA 95616
School of Vet Medicine-Equine Research Lab-Performance
Stover, S.; Gillis, C.; Shrkey, N.; Pool, R.
CORRELATION OF ULTRASONOGRAPHY, ANATOMY AND MECHANICAL PROPERTIES ON THE EQUINE SUPERFICIAL DIGITAL FLEXOR TENDON.
Abstract: The aim of this study is to investigate the relationships between the ultrasound image, the tendon anatomy and the mechanical properties of the tendons in young and aged horses. Results of this study will help improve the ability of veterinarians to interpret tendon sonograms.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Cardinet, G. H.; Valberg, S.; Tein, I.
INVESTIGATIONS OF LIPID METABOLISM IN EQUINE ATHLETES AND HORSES WITH TYING-UP SYNDROME.
Abstract: The tying-up syndrome is an important reason for poor performance in equine athletes. The purpose of this research is to broaden the scope of our clinical investigations of tying-up to include studies of abnormal fat metabolism in muscle. The identification of specific metabolic causes for tying-up will allow veterinarians to provide better advice to owners concerning diet, training programs, and genetic counseling.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Koblik, P.
MAGNETIC RESONANCE IMAGING (MRI) OF EQUINE TENDON.
Abstract: This project is evaluating a new method for assessing equine tendon. Similar to ultrasound, MRI may be developed for use in the live horse in the future. This study will evaluate the usefulness of MRI for detecting changes in mechanical function of the tendon and microscopic abnormalities.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Meagher, D. M.
ULTRASOUND OF EQUINE TENDONS OF HORSES IN RACE TRAINING.
Abstract: The flexor tendons of Thoroughbred horses were evaluated throughout the breaking and race training periods by ultrasound examination. A progression of ultrasound changes was identified that are believed to be a result of train- ing and accomodation to increasing exercise. This study provides important baseline information that is useful in separating normal physiologic ultrasound changes with changes associated with disease. Further study is directed at determining mechanical changes and microscopic appearance in stages of training.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Meagher, D. M.; Gillis, C.; Stover, S.; Pool, R.
MEASUREMENT OF RESPONSE OF EQUINE TENDONS TO TRAINING: UTILIZING MATERIALS TESTING EQUIPMENT TO DETERMINE INCREASES IN TENDON STRENGTH. ULTRASOUND TO DETERMINE INCREASES IN DIAMETER/INTERNAL STRUCTURE.
Abstract: Bowed tendons are a major cause of lameness in perfomance horses and the superficial digital flexor (SDF) is the tendon primarily involved. Preliminary data has raised the question: Does the decrease in tendon density after four months of training represent a decrease in tendon strength at this stage? Results from computer-aided analysis of the ultrasound scans, the micro- scopic examination and the materials testing will be correlated to evaluate tendon changes during training.
California, University of - Davis, CA 95616
School of Veterinary Medicine
O'Brien, T. R.
CHARACTERIZATION OF THIRD PHALANGEAL WING "FRACTURES" IN FOALS.
Abstract: "Fractures" of the wing of the coffin bone have recently been identified in young Thoroughbred foals, with a particularly high incidence at some farms in California and Kentucky. This project is the first to evaluate these lesions microscopically and compare the development of these lesions with the normal growth and development of the wing of the coffin bone in these young growing foals. This information will allow us to determine whether these lesions are pathologic fractures or abnormalities of development.
California, University of - Davis, CA 95616
School of Veterinary Medicine
O'Brien, T. R.
LOCATION OF TENDINOUS AND LIGAMENTOUS INSERTIONS OF THE EQUINE DISTAL FORELIMB ON RADIOGRAPHS.
Abstract: The sites of attachment of tendons and ligaments to bones of the fetlock and pastern regions of the forelimb of the horse were determined and mapped onto normal radiographs of the distal forelimb. Visual aids of these mapped radiographs will be extremely useful to the practicing equine veterinarian. Veterinarians can then determine the likely tendon and ligamentous pathology associated with bony lesions at sites of tendon and ligament attachment observed on radiographs.
California, University of - Davis, CA 95616
School of Veterinary Medicine
O'Brien, T. R. (Dr. K. Berry-North Carolina State Univ.)
THE SIGNIFICANCE OF RADIOLUCENCY ON THE FLEXOR RADIOGRAPHIC VIEW OF THE NAVICULAR BONE.
Abstract: This study suggests that the cystic radiolucent lesion is more likely associated with remodeling in the subchondral bone of the flexor cortex and not necessarily with lesions of the flexor cortex and adhesions to the deep flexor tendon. This study is also providing information on the adaptations of the navicular bone during life.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Pool, R. R.
CORRELATION OF THE ULTRASOUND APPEARANCE OF EQUINE TENDON WITH MECHANICAL STRENGTH AND MICROSCOPIC APPEARANCE.
Abstract: Bowed tendons are a significant problem of the racing industry. In recent years we have obtained the ability to visualize tendons clinically by ultrasound examination. However, it is not clear how to interpret the ultrasound images. This study will compare the ultrasound appearance of the tendon in the live horse with the tendon's mechanical strength and elasticity. Results of this study will provide valuable information for the interpretation of ultrasound findings.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Pool, R. R.
PATHOGENESIS OF NAVICULAR DISEASE IN THE HORSE.
Abstract: This project is evaluating the events progressing to navicular disease in the Thoroughbred horse with special emphasis on the biomechanical (traumatic) factors that lead to disease. Knowledge of these events will allow us to suggest factors (e.g. hoof conformation, shoeing) that may reduce the likelihood or the degree of navicular disease obtained by horses.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Pool, R. R.
PATHOGENESIS OF THIRD CARPAL BONE SLAB FRACTURES IN THE THOROUGHBRED RACEHORSE.
Abstract: Although slab fractures of the third carpal bone in the knee (carpus) occur suddenly, they result from the culmination of longer standing underlying disease of the parent carpal bone. The project is looking at the third carpal bones from racing Thoroughbred horses that died and were examined at the California Veterinary Diagnostic Laboratory System. This opportunity allows us to study the early stages of disease in horses of known age and racing history and understand how this disease comes about and leads to slab fracture.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Pool, R. R.; Stover, S.; Gillis, C.; Willits, N.
A STUDY OF THE TYPES OF INJURIES AND THEIR LOCATIONS AFFECTING JOINT SURFACES OF THE FORELIMBS OF RACING THOROUGHBRED HORSES BEING NECROPSIED AT CVDL.
Abstract: This project will document and characterize the pattern of structural alterations (lesions) occurring in joint surfaces of the forelimbs of racing Thoroughbred horses that were brought to CVDL at UC Davis for necropsy. The study will provide the first epidemiologic study of joint disease occurring in the joints of forelimbs from elbow to foot in Thoroughbred racehorses being euthanized or dying at the track because of severe injuries to the musculo- skeletal system or diseases of other organ systems.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
BONE REMODELING IN HORSES WITH CUSHINGS DISEASE.
Abstract: This project is evaluating the microscopic appearance of horses with and without naturally occurring Cushings Disease. Because horses with Cushings Disease have abnormalities in their naturally occurring corticosteroid levels, we hope to correlate any changes we find with circulating corticoster- oids. Steroids are associated with bone loss in humans and other species of animals. We are concerned this may also be true in the horse.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
BUCKED SHINS AND REMODELING OF THE CANNON BONE IN RACING AND TRAINING THOROUGHBRED HORSES.
Abstract: Cannon bones obtained from Thoroughbred horses in race training that died or were euthanized at California Racetracks and were examined by the California Veterinary Diagnostic Laboratory System are being utilized. Visible and microscopic changes that occur due to age and racing history are being com- piled. This information will enhance our understanding of the normal "physio- logic" changes that a horse undergoes related to either aging or training alone and enhance our ability to differentiate onset of disease from normal growth.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
BUCKED SHINS AND STRESS FRACTURES IN CALIFORNIA THOROUGHBRED RACING HORSES.
Abstract: Bucked shins and/or stress fractures occur in the cannon bone of over 70% of racing Thoroughbred horses. Although the pain and decreased per- formance exhibited by affected horses are well known, the changes in the cannon bone which lead to bucked shins and fractures are not clearly understood. Cannon bones from 90 horses which died at California racetracks will provide a unique opportunity for study of the early and progressive structural abnormali- ties occurring in California Thoroughbred racehorses.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
BUCKED SHINS AND STRESS FRACTURES IN THE THOROUGHBRED RACEHORSE.
Abstract: The cannon bones from Thoroughbred horses trained routinely for racing and that developed bucked shins were evaluated by microscopy and materials testing to better understand the initial events leading to disease. The project will attempt to determine whether training related remodeling and increased porosity in the bone is a major predisposing factor to disease, or whether microfractures occur in otherwise normal bones.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
CORRELATION OF ULTRASONOGRAPHY, ANATOMY AND MECHANICAL PROPERTIES OF THE EQUINE SUPERFICIAL DIGITAL FLEXOR TENDON.
Abstract: The tendons of a living horse can be visualized using ultrasound, but the interpretation of the ultrasound image in terms of the anatomy, strength and health of the tendon has not been clearly established. We propose to investigate the relationships between the ultrasound image, the tendon anatomy, and the mechanical properties of the tendons in foals and young and aged horses. analysis of the results should greatly improve our ability to interpret tendon sonograms with respect to anatomy, strength and stiffness of tendons.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
DEVELOPING OF A MODEL DESCRIBING THE BIOMECHANICS OF THE EQUINE METACARPUS USING FINITE ELEMENT TECHNIQUES.
Abstract: The goal of this project is to develop a computer stimulation of the cannon bone for the future study of diseases of the cannon bone, such as splint bone abnormalities, fractures, and bucked shins. Data obtained from computed tomography scans of cannon bones, and data obtained from materials testing of bone specimens from the cannon bone will be used with engineering computer software to describe the biomechanics of the bone. This model will be validated by comparison of the microscopic structure of the bone.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
EFFECT OF LOCATION AND AGE ON BONE APPOSITIONAL RATE IN FOALS.
Abstract: The mechanical strength of bone tissue is related to the type of bone tissue that a horse lays down at sites of growing bone and sites of bone repair. We believe one of the factors that determines the type of bone laid down is the rate at which the bone is laid down. This project will determine the rates of bone growth possible in growing foals.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
EVALUATION OF A NEW FIXATOR DESIGN FOR THE DISTAL LIMB OF THE HORSE.
Abstract: This study has developed a new configuration for an external fixator with the likelihood of better understanding the weightbearing loads of the horse. This new configuration will be tested on cannon bones obtained from horses dying from other causes, and compared to currently used techniques. An improved fixator would enhance our ability to treat fractures and ligamentous ruptures of the lower limb of the horse (for example, comminuted phalangeal fractures and suspensory apparatus ruptures; severe sesamoid ligament/bone inj.)
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
IDENTIFICATION OF NOVEL MEDIATORS OF EQUINE ARTHRITIS AND EVALUATION OF CURRENT THERAPEUTIC AGENTS.
Abstract: Identifying new mediators of equine cartilage destruction will be of fundamental importance to enable investigation of novel clinical approaches to these problems and to evaluate the best current methods of treatment. Establishing an in vitro model of equine cartilage metabolism will have extensive future applications to understanding the normal and pathological maintenance of this tissue.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
INCORPORATION OF AUTOGENOUS STERNAL OSTEOCHONDRAL GRAFTS TO ENHANCE HEALING OF JOINT DEFECTS IN THE HORSE.
Abstract: Injuries to joint surfaces are known to heal very poorly. This study evaluates a promising technique that utilizes cancellous bone and cartilage obtained from the sternum and grafted onto the injured joint surface. The benefits of this technique include the replacement of injured tissue with tissues from the same horse, replacement of joint tissues by tissues very similar in appearance and function to normal joint tissues, and sparing of other normal joint surfaces in the same horse.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
REMODELING PARAMETERS OF EQUINE CORTICAL AND CANCELLOUS BONE.
Abstract: This project is determining baseline normal values for bone re- modeling parameters in the horse. This information will be used for comparison with values obtained with horses with suspected bone disease. It will enhance our ability to definitely diagnose and categorize metabolic and nutritional bone disease of horses, and allow for scientific study of these diseases.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
THE ASSOCIATION OF INCOMPLETE STRESS FRACTURES WITH COMPLETE FRACTURES OF THE HUMERUS IN RACEHORSES.
Abstract: Nineteen horses were euthanized for complete fracture of the humerus obtained during racing or training. The fractured humerus was examined in detail from 11 of these horses. Of these 11 humeri, 9 were found to have previous incomplete stress fracture of the humerus that created a weak spot and predisposed to complete fracture under otherwise normal training conditions. The complete racing history is being obtained to determine if incomplete stress fractures can be detected in time for training to be stopped until healed.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
THE EFFECT OF DEMINERALIZED BONE MATRIX ON BONE INDUCTION IN THE HORSE.
Abstract: Proteins within bone contain factors that induce cells of an animal to produce bone tissue. This study is evaluating the potential of a deminera- lized horse bone preparation to stimulate the production of bone tissue. A preparation like this has many applications; for example, the stimulation of bone at the sites of fracture repair. Advantages to this approach include the ability to use preparations obtained in abundance from bones of horses that died for other reasons in fracture repair without stimulation immunologic reactions.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
THE EFFECT OF LOADING ON THE HEALING OF OSTEOCHONDRAL DEFECTS.
Abstract: This study is directed at determining the factors responsible for the poor healing of joint surface injuries. Because of their unique anatomy of the fetlock joint, this study was performed in sheep. It evaluated the effect of weightbearing on the healing of defects created in joint surfaces. This study will determine if mechanical load inhibits healing of joint surface injuries.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
THE RESPONSE OF EQUINE ARTICULAR CARTILAGE TO FACTORS THAT PROMOTE DEGENERATIVE JOINT DISEASE.
Abstract: Degenerative joint disease (arthritis) is thought to occur as a result of inflammatory molecules produced by the joint capsule and synovial membrane. The effect of these substances is being evaluated in vitro in cultures of cartilage from the joint surfaces of horses. This important work will lead to the testing of drugs that are believed to attentuate the progression of arthritis and/or promote healing of diseased joints. These studies will provide an accurate and useful means for testing drugs being used.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.
VERIFICATIONS OF COMPUTER-GENERATED STRAIN DISTRIBUTION IN THE EQUINE METACARPUS USING IN IN VITRO STRAIN MEASUREMENTS.
Abstract: Diseases of the metacarpus, including the bucked shin complex, splint bone fracture, and cannon bone fractures, are common diseases of young racing animals and cost the equine industry a great deal in terms of lost training time and the occassional loss of valuable animals. Data obtained from this study will be used to help validate the accuracy of three-dimensional finite-element computer models of the equine metacarpus now being developed.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M. (Dr. Hawkins - University of Florida)
OSTEOPOROSIS IN BROODMARES IN LATE GESTATION.
Abstract: Clinically it has been noted that broodmares heavily in foal have a higher likelihood of completely fracturing a long bone than nonpregnant mares. This project is examining the porosity and mineralization of long bones from mares that died during the last portion of pregnancy. Initial observations suggest that bones from these mares are weaker than bones of nonpregnant mares. This may result from the drain that the growing fetus has on the bone mineral of the mare.
California, University of - Davis, CA 95616
School of Veterinary Medicine
Stover, S. M.; Taylor, D. S.
EVALUATION OF A NEW METHOD OF REPAIR FOR FORELIMB FRACTURES AND BREAKDOWNS.
Abstract: Fractures of the cannon bone and pastern region, as well as "break- downs" of the suspensory apparatus and flexor tendons are often not amenable to repair by casting or surgery. These conditions often could benefit from a device called an external skeletal fixor used to stabilize the fracture fragments and support the lower portion of the limb. This study will evaluate a new pin placement pattern for an external skeletal fixor configuration which will be stronger by allowing more, smaller pins to share in load distribution.
California, University of - Davis, CA 95616
School of Veterinary Medicine VM: Anatomy, Physiology, and Cell Biology
Stover, S.; Haussler, K.; Hawkins, D.; Sharkey, N.
FUNCTIONAL ANATOMY AND PATHOLOGY OF THE SACROILIAC JOINT IN PERFOMANCE HORSES.
Abstract: NOT REPORTED.
California, University of - Davis, CA 95616
School of Veterinary Medicine VM: Anatomy, Physiology and Cell Biology
Stover, S.; McDuffee, L.
DYNAMIC BIOMECHANICAL PERFORMANCE OF THE EQUESTRIAN INTRAMEDULLARY INTERLOCKING NAIL FOR FIXATION OF A MIDSHAFT OSTEOTOMY OF THE ADULT HORSE.
Abstract: NOT REPORTED.
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Anatomy
Stover, S.M.; McDuffee, L.A.; Taylor, K.
AN IN VITRO BIOMECHANICAL INVESTIGATION OF THE INTER-LOCKING NAIL FOR FIXATION OF A MIDSHAFT OSTEOTOMY OF THE TIBIA OF ADULT HORSES.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Anatomy
Stover, S.M; Taylor, K.
INVESTIGATION OF INCOMPLETE HUMERAL STRESS FRACTURE IN RACE HORSES.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Anatomy/Zoology
Stover, S.M.; Benton, H.P.; Cheng, T.C.
STRESS PROTEINS IN EQUINE DEGENERATIVE JOINT DISEASE.
Abstract: Much of the attention to the mechanisms of degenerative joint disease have focused of the health of the cartilage matrix. However, after severe damage the integrity of the cellular components must be considered. This project has focused on understanding the response of cartilage cells to extreme adverse conditions. We have defined which known "stress proteins" are synthesized in response to heat injury (as may occur in inflammation) or calcium stress (as may occur after membrane damage).
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Anatomy/Zoology
Stover, S.M.; Benton, H.P.; MacDonald, M.H.
ROLE OF POLYPEPTIDE GROWTH FACTORS IN INFLAMMATION AND TISSUE REPAIR OF ARTICULAR CARTILAGE AND SYNOVIAL MEMBRANE.
Abstract: Articular cartilage was maintained in vitro under conditions that allowed the study of the rate of degradation and new synthesis of cartilage matrix molecules. A number of known growth factors were tested for their ability to stimulate the production of a healthy matrix capable of withstanding the forces exerted during joint movement. These included platelet-derived growth factor, fibroblast growth factor, boen morphogenetic protein and epidermal growth factor. The response of horses to these factors was age-dependent.
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Diagnostic Lab
Case, J.T.; Stover, S.M.
RISK ASSESSMENT OF FACTORS ASSOCIATED WITH BREAKDOWNS IN CALIFORNIA RACE HORSES.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Radiology
O'Brien, T.R.; Koblik, P.D.; Kaneps, A.J.
CHARACTERIZATION OF DISTAL PHALANX SOLAR MARGIN LESIONS IN THOROUGHBRED FOALS USING COMPUTED TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Veterinary Medicine - VM: Surgery
Pascoe, J.R.; Snyder, J.R.; Vatistas, N.J.
COMPARE THE RESULTS OF A MODIFICATION OF THE MEDIAL PATELLAR LIGAMENT DESMOTOMY WITH THE STANDARD TECHNIQUE.
Abstract: NOT REPORTED
California, University of - Davis, CA 95616
School of Veterinary Medicine-Equine Research Lab
Bernoco, D.
SEARCH FOR DIFFERENCES IN SODIUM CHANNEL DNA BETWEEN NORMAL AND HYPERKALEMIC PERIODIC PARALYSIS (HYPP) AFFLICTED QUARTER HORSES.
Abstract: The aim of this proposal is to determine if HYPP in Quarter Horses is caused by the same gene that has been found to be responsible in human HYPP and to perfect a simple test to detect the gene causing the disease.
California, University of - Davis, CA 95616
School of Veterinary Medicine-Equine Research Lab
Spier, S.; Bernoco, D.; Carlsen, R.; Carlson, G.
HYPERKALEMIC PERIODIC PARALYSIS IN QUARTER HORSES: DETERMINATION OF THE MODE OF INHERITANCE AND IDENTIFICATION OF THE MUSCLE MEMBRANE DEFECT.
Abstract: The purpose of this study is to better understand what happens during an attack, what precipitates the attacks, and how to treat and prevent attacks in horses with this disease. The genetics of the disease will be studied to document the mode of inheritance (dominant or recessive).
California, University of - Davis, CA 95616
VM: Anatomy, Physiology and Cell Biology
Stover, S.; Carrier, T.; Gardner, I.; Estberg, L.; Johnson, B.
INVESTIGATION OF AN ASSOCIATION BETWEEN PERIODS OF INACTIVITY (LAY-UP) IN THOROUGHBRED RACEHORSES AND THE POTENTIAL RISK FOR STRESS FRACTURE RELATED INJURIES.
Abstract: NOT REPORTED.
California, University of - Davis, CA 95616
VM: ANATOMY, PHYSIOLOGY AND CELL BIOLOGY
Stover, S.; Galuppo, L.
AN IN VITRO BIOMECHANICAL COMPARISON OF TWO INTRAMEDULLARY NAILING TECHNIQUES FOR REPAIR OF THIRD METACARPAL BONE FRACTURES IN HORSES.
Abstract: NOT REPORTED.
California, University of - Davis, CA 95616
VM: Dept. Anatomy, Physiology, & Cell Biology
Stover, S. M.
RISK ASSESSMENT OF HOOF BALANCE AND SHOEING FACTORS ASSOCIATED WITH FATAL MUSCULOSKELETAL BREAKDOWN IN RACEHORSES.
Abstract: The objective of this study is to identify types of hoof conformation and shoeing that increase the risk of serious injuries to racehorses. Recommendations could be made for the prevention of some serious injuries by correcting some types of poor hoof conformation and avoiding some types of horseshoeing techniques. Information from this study will be used to prevent musculoskeletal injuries in racehorses, thereby, increasing the safety of horse racing for horse, rider and decreasing economic loss to the industry.
California, University of - Davis, CA 95616
VM: Surgical and Radiological Sciences
Kaneps, A.; Seibert, J.; Wisner, E.
BONE DENSITY DETERMINATION OF THE EQUINE THIRD METACARPUS BY DIGITIZATION OF PLAIN-FILM RADIOGRAPHS.
Abstract: NOT REPORTED.
California, University of - Davis, Ca. 95616
Hildebrand, S.
A NEW MUSCLE RELAXANT - ATRACURIUM BESYLATE: NEUROMUSCULAR AND CARDIOVASCULAR EFFECTS IN HEALTHY ADULT HORSES ANESTHETIZED WITH HALOTHANE.
Abstract: NOT REPORTED
California, University of - Davis, Ca. 95616
Meagher, D.; Pryor, P.
TO INVESTIGATE THE CONTRIBUTION TO FETLOCK AND COFFIN JOINT FUNCTION PROVIDED BY THE SUPERFICIAL DIGITAL FLEXOR TENDON, DEEP DIGITAL FLEXOR TENDON, AND SUSPENSORY LIGAMENT OF THE EQUINE FORELIMB.
Abstract: NOT REPORTED
California, University of - Davis, Ca. 95616
Pascoe, J.; Fischer, A.; Stover, S.
HEALING OF FULL THICKNESS CARTILAGE DEFECTS IN THE HORSE: A COMPARISON OF WEIGHT-BEARING TO NON-WEIGHT-BEARING AREAS.
Abstract: NOT REPORTED
California, University of - Davis, Ca. 95616
Dept. of Surgery
Pascoe, J.; Lloyd, K.; Stover, S.
EFFECT OF SYNOVIAL FLUID AND THE PHARMACOKINETICS OF GENTAMICIN AFTER THE INTRA-ARTICULAR ADMINISTRATION OF GENTAMICIN SULFATE AND SODIUM BICARBONATE.
Abstract: NOT REPORTED
Cambridge, University of - Cambridge CB3 0ES
School of Veterinary Medicine
Jeffcott, L. B.
PATHOGENESIS OF OSTEOCHONDROSIS: THE ROLE OF TYPE VI COLLAGEN.
Abstract: NOT REPORTED.
Cambridge, University of - Madingley Road, Cambridge CB# OES
Dept. of Clinical Vet Medicine
Jeffcott, L.B.; Collins, J.A.
DIAGNOSTIC IMAGING FOR BACK PROBLEM.
Abstract: Clinical diagnosis of poor performance due to back problems is often difficult and non specific. The use of nuclear scintigraphy has been particularly helpful to identify regions of the spine for further investigation both clinically by use of radiography and ultrasonography. A series of 100 referred horses that were subjected to a standard protocol, including scintigraphy, are currently being written up. Further studies and the cor- relation of diagnostic imaging changes with pathological findings are underway.
Cambridge, University of - Madingley Road, Cambridge CB# OES
Dept. of Clinical Vet Medicine
Jeffcott, L.B.; Graham, C.
INVESTIGATION OF SPINAL MOVEMENT IN RELATION TO CONFORMATION.
Abstract: This project plans to develop a reproducible method for examining movement activity in the spine of normal horses. Specific objectives include: 1) The investigation of the normal functional anatomy and noninvasive three dimensional kinematics of the horse's spine; 2) The development of a grading scheme to evaluate pain and flexibility of the spine in horses with back problems; 3) To use this scheme to assist in evaluating clinical progress and the effects of different treatment regimes.
Cambridge, University of - Madingley Road, Cambridge CB# OES
Dept. of Clinical Vet Medicine
Jeffcott, L.B.; Henson, F.M.D.; Hernandez, V.G.; Shingleton, W.D.; Voute, L.C.
DEVELPMENTAL ORTHOPAEDIC DISEASE - DYSCHRONDROPLASIA (OSTEOCHONDROSIS) IN THE HORSE.
Abstract: The general aim of the equine developmental orthopedic disease group is to study the cellular and molecular mechanisms occurring during the development of dyschondroplasia (osteochondrosis) in order to identify the pathogenesis of the disorder. The specific projects being undertaken are: 1) Extracellular matrix research; 2) growth factor research.
Cambridge, University of - Madingley Road, Cambridge CB# OES
Dept. of Clinical Vet Medicine
Murray, R.C.
APPLICATION OF ALTERNATIVE INSTRUMENTATION FOR INTERNAL FIXATION OF EQUINE FRACTURES.
Abstract: Instumental for internal fixation of articular fractures is available for use in humans which is not applied in the horse. Biomechanical evaluation and clinical assessment of instrumentation methods are being undertaken which may assist in elimination of some of the obstacles to management of equine articular fractures.
Cambridge, University of - Madingley Road, Cambridge CB# OES
Dept. of Clinical Vet Medicine
Murray, R.C.
CARPAL OSTEOCHONDRAL PATHOLOGY.
Abstract: Osteochondral injury of the carpal cuboidal bones is a common prolbem which can terminate a horse's career. The investigators have demonstrated topographical variation in the biomechanical properties of equine intercarpal articular cartilage in normal horses. Current work includes investigation into equine intercarpal articular cartilage biomechanical properties and histochemistry, and their relationships with subchondral bone mineral density, and the effects of intra-articular and systemic medication.
Return To Database Index
|
|
|
|
|
